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While glutathione is available in oral supplements and topical formulations, its most effective and bioavailable form is through intravenous (IV) injections
Glutathione: A typical treatment plan consists of 8 to 10 sessions, spaced weekly or bi-weekly depending on the individual’s skin concerns, health goals, and response to the therapy.
With celebrity wellness trends in the spotlight, the tragic passing of Shefali Jariwala, who reportedly received IV glutathione injections on a day she was fasting, has cast a somber reflection on the risks associated with unsupervised anti-ageing regimes; on June 27, 2025, the popular actress suffered a sudden cardiac arrest, sparking a broader conversation about the safety of high-dose antioxidant treatments.
Glutathione is often referred to as the “master antioxidant” for its powerful role in protecting cells from oxidative stress, aiding detoxification, and strengthening the immune system. Naturally produced by the liver, it’s made of three amino acids—glutamine, glycine, and cysteine—and plays an essential role in maintaining cellular health and vitality.
Over time, glutathione has become a sought-after ingredient in aesthetic and wellness treatments, especially for its skin-brightening, anti-aging, and rejuvenating effects.
Dr. Amit Gupta, Cosmetic Surgeon and Founder & Director of Aeona, shares all you need to know:
How Is Glutathione Administered?
While glutathione is available in oral supplements and topical formulations, its most effective and bioavailable form is through intravenous (IV) injections. Administered under medical supervision typically in a hospital or clinical setting, this method allows for direct absorption into the bloodstream, delivering faster and more noticeable results.
A typical treatment plan consists of 8 to 10 sessions, spaced weekly or bi-weekly depending on the individual’s skin concerns, health goals, and response to the therapy.
Because there is a small chance of allergic reactions, medical supervision is crucial. Trained professionals monitor each session to ensure patient safety and promptly manage any potential side effects.
Key Benefits of Glutathione Therapy
1. Skin Brightening and Even Tone
Glutathione inhibits the production of melanin—the pigment responsible for dark spots and uneven skin tone. This results in a brighter, clearer complexion over time, making it a popular choice for those seeking fairness or glow-enhancing treatments.
2. Anti-Aging Effects
As a potent antioxidant, glutathione fights free radicals that damage skin cells and accelerate aging. Regular treatments help reduce fine lines, wrinkles, and dullness, promoting firmer, more youthful-looking skin.
3. Powerful Detoxification
Glutathione plays a critical role in flushing out heavy metals, toxins, and pollutants from the body, especially from the liver. This not only boosts overall health but also improves skin clarity.
4. Enhanced Immunity and Healing
By repairing damaged cells and supporting immune function, glutathione strengthens the body’s defenses and improves recovery from environmental and lifestyle stressors.
5. Improved Energy and Well-Being
Many patients report feeling more energetic, mentally alert, and revitalized after completing a glutathione course, thanks to its deep cellular impact.
Risks and Considerations
While glutathione therapy is generally considered safe, it is not recommended for individuals with kidney disorders or compromised renal function. Such patients must avoid this treatment to prevent complications.
Mild and temporary side effects may include:
Nausea
Vomiting
Mild headaches or dizziness (rare)
These symptoms typically subside on their own and are not a cause for concern. A thorough medical consultation is essential before beginning treatment to rule out any contraindications.

Swati Chaturvedi, a seasoned media and journalism aficionado with over 10 years of expertise, is not just a storyteller; she’s a weaver of wit and wisdom in the digital landscape. As a key figure in News18 Engl…Read More
Swati Chaturvedi, a seasoned media and journalism aficionado with over 10 years of expertise, is not just a storyteller; she’s a weaver of wit and wisdom in the digital landscape. As a key figure in News18 Engl… Read More
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